Marijuana Research Points to Concerns on Adolescent Brain Development

Marijuana legalization, now found in seven states and in Washington, D.C., has added sizably to the challenge of drug prevention. According to the most recent Monitoring the Future Survey, an annual study of youth drug use and other at-risk behaviors, fewer than 40% of teens consider marijuana use to be risky.

In the online publication “Science News for Students,” Christopher Hammond, a child and adolescent psychiatrist at Johns Hopkins University School of Medicine in Baltimore, Md., noted how Colorado’s legalization and its accompanying advertising campaign have enticed more youth there to try marijuana and that some of them are now regular users. He said, “When you start to use it regularly as a teenager, it has harmful consequences.” Several studies have shown brain changes in regular teen users of pot, including reduced brain volume in areas of the brain that  process information.

Yet another authority on the subject is Dr. Ellen Rome, head of the Center for Adolescent Medicine, Cleveland Clinic Children’s Hospital. She cited the long-lasting ill-effects of marijuana use on the structure and function of still developing brains: “Marijuana use affects the healthy formation of the prefrontal cortex and can interfere with the brain’s ability to transfer information from short term to long term memory.”

PDFNJ encourages New Jersey legislators to familiarize themselves with the considerable body of research on how marijuana impacts the developing brain of adolescents, and how legalization of marijuana impacts the attitudes and behaviors of adolescents.

 

from sciencenewsforstudents.org:

Legalizing pot may confuse teens into thinking it’s safe

 
States that allow adults to use marijuana may send a risky message to teens, new data indicate
 
 
APR 12, 2017 — 7:10 AM EST
 
 
 
marijuana leaf and cannabis plants
 

A growing number of teens think marijuana is no big deal, a new study finds. And that may encourage many to experiment with its use.

 

OPENRANGESTOCK/ISTOCKPHOTO

 

A high school English teacher in New York — let’s call her Ms. McDonald — has lately noticed more kids coming to class high on marijuana. She can tell. When they’re high, they’re spacey and unfocused, she says. Plus, she adds, “They talk pretty openly about it. It’s considered very normal.”

Normal? What gives teens that idea, asks Magdalena Cerdá. She works at the University of California, Davis School of Medicine, in Sacramento. As an epidemiologist, she tracks down causes of disease or unhealthy trends.

Marijuana use by kids certainly is not healthy, notes Stephen Wallace. He directs the Center for Adolescent Research and Education in Palm Beach Gardens, Fla. Some teens who regularly use pot develop mental-health problems, Wallace notes. These could include anxiety, depression and even psychosis (Sy-KOH-sis). That last condition is where people can’t tell what is real and what they are imagining.

Other problems linked to using pot include making working memory worse, he points out. Working memory is a brain function we need to understand language. It also helps us remember — for example — a math formula long enough to use it to do homework. Bad working memory can therefore lead to bad grades.

Yet if adolescents think pot is “no big deal,” Cerda wondered, might they become more likely to use it? In search of answers, she started reading research studies. They showed that compared to 25 years ago, fewer adolescents now think marijuana use is risky.

Cerdá knew that some states were making marijuana legal. Nineteen states allow adults to buy pot with a doctor’s prescription. Seven states have made non-medical use legal. That means adults can buy it as they would alcohol.

These laws only apply to adults. Buying and using pot is still illegal for minors. But Cerdá wondered how the new laws might be affecting teen attitudes and use of the drug. To find out, her team started its own study.

Based on a quarter-million U.S. teens

Her team used a survey called Monitoring the Future. Researchers collect data for it every year. They ask eighth, tenth and twelfth graders in U.S. schools about their use of, and attitudes about, alcohol and other drugs. Cerdá’s team focused on data from 253,902 students in the states of Washington and Colorado. Both of these states legalized non-medical use of marijuana in 2012. The team looked at the years 2010 through 2015. This let them concentrate on use and attitudes before and after pot became legal.

First, Washington: After 2012, a sense that this drug was risky went down among eighth and tenth graders. It fell by an average of 15 percent. In states where pot stayed illegal, the sense that it was risky went down by an average of only 6 percent among students in those grades. After the Washington law changed, the number of teens who used pot in the month before they had been surveyed increased 2 percent among eighth graders. It increased 4.1 percent among tenth graders.

This pattern bucked a trend seen in states where the drug stayed illegal. There, pot use dropped by 1.3 percent among eighth graders. It dropped by almost 1 percent among tenth graders.

There was no change in the drug's use or attitudes among high-school seniors in Washington. The researchers have a theory about why. Maybe these older teens had already made up their minds about pot.

Cerdá’s team also saw no real change in attitudes on pot among students of any age in Colorado. This could have to do with how Colorado legalized the use of medical marijuana in 2000, Cerdá says. Kids saw posters and TV ads about the issue. This may have given them the idea that pot was normal and beneficial. By the time the drug's non-medical use was legalized, the kids’ attitudes may already have been shaped by its legal medical use.

The results of Cerdá’s study appear in the February JAMA Pediatrics.

What’s good for adults may not be good for teens

Cerdá hopes states will try not to make pot seem glamorous. “Research shows that non-attractive labels around tobacco were important” to keep kids off cigarettes, she says. “Maybe some of these same lessons should be applied to marijuana.”

Christopher Hammond agrees. He’s a child and adolescent psychiatrist at the Johns Hopkins University School of Medicine in Baltimore, Md. “When Colorado legalized medical marijuana use, they allowed for advertising,” he notes. He now thinks that may have made teens open to trying it. That could have led to them use pot regularly.

medical marijuana
When kids learn their state has approved the medical use of marijuana, they may see it as less dangerous than other illegal drugs. But pot can have dangerous effects on the teenage mind and body.
wingedwolf/iStockphoto

And what's disturbing, he notes: “We don’t have any information on who can experiment with marijuana and not go on to develop problems.”

Hammond, too, worries about kids using pot. Some marijuana use may have positive effects for adults, he says. But he adds, “When you start to use it regularly as a teenager, it has harmful consequences.” Several studies have shown brain changes in regular teen users of pot. These include lower brain volume in regions used to process information. The consequences could be long lasting. “Your brain doesn’t stop developing when you’re 18,” says Hammond. It matures into your late 20s. Some of those still-maturing parts “are the regions we know are more sensitive to marijuana exposure,” Hammond says.

For these and a host of other reasons, Wallace would like fewer teens to think pot is safe. He’d also like to see a drop in the number of them who use it.

Early pot use can affect a person’s ability to think and focus. It can make it hard to plan and multitask. It can harm short-term memory and lower IQ in regular teen users, says Hammond. Plus, he adds, “It’s unclear if that drop in IQ ever catches back up if you stop using.”

The drug also can be addictive. Leslie Walker-Harding heads pediatrics at Penn State Children’s Hospital in Hershey, Pa. Four in 10 people who use pot as kids develop a drug-abuse problem, she notes. That rate is four times higher than is seen in adult users.

For all of these reasons, when people ask Wallace, “What level of use is acceptable among young people?” he answers “zero!”

More states are set to legalize pot. This has experts wondering how to change the way teens think about it. Getting rid of attractive ads might help. And for middle- and high school students, Cerdá adds, “States should maybe think about investing in evidence-based substance-abuse programs." She thinks that might help protect vulnerable kids from the risks of drug use.

When it comes to pot, her message is simple: “Just because it’s legal doesn’t mean it’s good for you.”

 

Power Words

(for more about Power Words, click here)

addicted     Unable to control the use of a habit-forming drug or to forego an unhealthy habit (such as video game playing or phone texting). It results from an illness triggered by brain changes that occur after using some drugs or engaging in some extremely pleasurable activities. People with an addiction will feel a compelling need to engage in some behavior, such as using a drug (which can be alcohol, the nicotine in tobacco, a prescription drug or an illegal chemical such as cocaine or heroin) — even when the user knows that doing so risks severe health or legal consequences.

adolescence     A transitional stage of physical and psychological development that begins at the onset of puberty, typically between the ages of 11 and 13, and ends with adulthood.

anxiety    A nervous reaction to events causing excessive uneasiness and apprehension. People with anxiety may even develop panic attacks.

average     (in science) A term for the arithmetic mean, which is the sum of a group of numbers that is then divided by the size of the group.

behavior     The way a person or other organism acts towards others, or conducts itself.

depression      (in medicine) A mental illness characterized by persistent sadness and apathy. Although these feelings can be triggered by events, such as the death of a loved one or the move to a new city, that isn’t typically considered an “illness” — unless the symptoms are prolonged and harm an individual’s ability to perform normal daily tasks (such as working, sleeping or interacting with others). People suffering from depression often feel they lack the energy needed to get anything done. They may have difficulty concentrating on things or showing an interest in normal events. Many times, these feelings seem to be triggered by nothing; they can appear out of nowhere.

drug abuse     A term for the condition where people may become dependent or even addicted to alcohol, tobacco or other types of drugs (either street drugs or prescription medications). These people do not use drugs to treat a medical condition but as an unhealthy way to alter the way they think, feel or respond to outside stimuli.

epidemiologist     Like health detectives, these researchers figure out what causes a particular illness and how to limit its spread.

high school     A designation for grades nine through 12 in the U.S. system of compulsory public education. High-school graduates may apply to colleges for further, advanced education.

marijuana     A mind-altering drug. It is made from the leaves (and sometimes stems or seeds) of the Cannabis sativa plant. This drug also goes by the colloquial terms pot and weed.

minors     Children and adolescents below an age that would make them legally adults.

pediatrics     A field of medicine that has to do with children and especially child health. A doctor who works in this field is known as a pediatrician.

perception     The state of being aware of something — or the process of becoming aware of something — through use of the senses.

psychosis      A potentially frightening symptom associated with some types of mental illness. In it, someone loses the ability to recognize what is real. Affected people may claim to see, hear or believe things that aren’t real. They may also develop strange thoughts, behaviors and feelings — such as being convinced that someone is out to get them.

risk     The chance or mathematical likelihood that some bad thing might happen. For instance, exposure to radiation poses a risk of cancer. Or the hazard — or peril — itself. Among cancer risks that people can face are radiation and drinking water tainted with arsenic.

short-term memory     (also known as primary memory) The small amount of memory held actively in the mind for a short period of time, such as the series of digits in a telephone number.

survey     (v.) To ask questions that glean data on the opinions, practices (such as dining or sleeping habits), knowledge or skills of a broad range of people. Researchers select the number and types of people questioned in hopes that the answers these individuals give will be representative of others who are their age, belong to the same ethnic group or live in the same region. (n.) The list of questions that will be offered to glean those data.

working memory    The ability to hold something in the mind for a short period of time and to adapt it for use, such as hearing a sequence of numbers, then reciting them backwards.

 
 

Citation

Journal: M. Cerdá et al. “Association of state recreational marijuana laws with adolescent marijuana use,” JAMA Pediatrics. Vol. 171, February 2017, p. 142.  doi:10.1001/jamapediatrics2016.3624.

Journal: J. Jacobus and S.F. Tapert. Effects of Cannabis on the adolescent brainCurrent Pharmaceutical Design. Vol. 20, 2014, p. 2186. doi: 10.2174/13816128113199990426.

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